Current Status of COVID-19 Vaccine Candidates in Phase 3 Trials in the World

Research started with the pneumonia cases that emerged in Wuhan, China in December 2019 and whose cause could not be determined clearly, revealed the existence of a new type of coronavirus The infectious agent was named SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2), and the disease setting caused by the virus was entitled COVID-19 (coronavirus disease-2019) The increasing number of cases and mortality rates due to the disease worldwide has caused a large number of vaccine research studies to be initiated simultaneously According to the World Health Organization (WHO) December 22 nd 2020 data, the number of Covid-19 vaccine research studies currently ongoing all over the world is 233 and the number of studies that have passed the clinical trials stage is 61 15 of these studies are at Phase 3 stage There are 12 ongoing COVID-19 vaccine studies in our country and all of them are in the predinkal stage In this review article, 15 vaccine candidate studies whose Phase 3 stage continues, were discussed among the COVID-19 vaccine research studies