Formation of compounds with P–C–N moiety by microwave-assisted condensations

Organophosphorus compounds containing the P-C-N moiety have been synthesized by microwave-assisted condensations. The synthesis of chiral -aminophosphonate and -aminophosphinate derivatives was studied using etyl octyl phosphite or alkyl phenyl-H-phosphinates. Amino-methylenebisphosphonates and amino-methylenebisphosphine oxides were also prepared by the three-component condensation of an amine, an orthoformate and the appropriate >P(O)H reagent. [GRAPHICS] .