Cost Analysis: In-house HSV PCR Capabilities

Introduction: HSV encephalitis has a worldwide incidence of about 500,000 persons per year with an overall mortality rate of 11-19% with treatment. While rare, HSV encephalitis is tested for frequently and empirically treated, especially in the neonatal population. HSV infection can be diagnosed with PCR, with most testing taking place at non-local facilities, often prolonging acyclovir exposure, hospital stay, and hospital costs. This study investigates if in-house HSV PCR testing decreases hospitalization, …