Dickkopf-Related Protein 2 is Epigenetically Inactivated and Suppresses Colorectal Cancer Growth and Tumor Metastasis by Antagonizing Wnt/β-Catenin Signaling

Can Wang,Yujuan Yue,Bianfei Shao,Zhu Qiu,Junhao Mu,Jun Tang,Xiaofan Han,Tingxiu Xiang,Guosheng Ren

Dickkopf-Related Protein 2 is Epigenetically Inactivated and Suppresses Colorectal Cancer Growth and Tumor Metastasis by Antagonizing Wnt/β-Catenin Signaling

2017

Can Wang
Yujuan Yue
Bianfei Shao
Zhu Qiu
Junhao Mu
Jun Tang
Xiaofan Han
Tingxiu Xiang
Guosheng Ren

Background/Aims: Aberrant activation of the Wnt/β-catenin signaling pathway plays a key role in the pathogenesis of multiple tumors including digestive cancers. R

Keywords:

Biochemistry
Wnt signaling pathway
Colorectal cancer
LRP6
Cancer research
Pathogenesis
Metastasis
Catenin
Biology
Signal transduction
LRP5
Methylation

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