Poloxamer gel adjuvant for O-typed foot and mouth disease polypeptides

The invention relates to a poloxamer gel adjuvant for O-typed foot and mouth disease polypeptides and a preparation method of the gel adjuvant. The gel adjuvant comprises 19-23 g of poloxamer 407, 1-8 g of poloxamer 188 and water. The preparation method comprises the following steps: adding part of deionized water into the poloxamer 407 and the poloxamer 188; refrigerating and stilling for complete dissolution; adding the rest deionized water; before using, adding O-typed foot and mouth disease polypeptide antigens till the concentration reaches 50 microgram/ml; shaking up. The poloxamer gel adjuvant prepared according to the invention has high immunological properties and good extracorporeal slow releasing properties.