Distinct Cell Clusters Touching Islet Cells Induce Islet Cell Replication in Association with Over-Expression of Regenerating Gene (REG) Protein in Fulminant Type 1 Diabetes

Kaoru Aida,Sei Saitoh,Yoriko Nishida,Sadanori Yokota,Shinichi Ohno,Xiayang Mao,Daiichiro Akiyama,Shoichiro Tanaka,Takuya Awata,Akira Shimada,Youichi Oikawa,Hiroki Shimura,Fumihiko Furuya,Soichi Takizawa,Masashi Ichijo,Sayaka Ichijo,Jun Itakura,Hideki Fujii,Akinori Hashiguchi,Shin Takasawa,Toyoshi Endo,Tetsuro Kobayashi

Distinct Cell Clusters Touching Islet Cells Induce Islet Cell Replication in Association with Over-Expression of Regenerating Gene (REG) Protein in Fulminant Type 1 Diabetes

2014

Background Pancreatic islet endocrine cell-supporting architectures, including islet encapsulating basement membranes (BMs), extracellular matrix (ECM), and possible cell clusters, are unclear.

Keywords:

Cell biology
Type 1 diabetes
Cell
Cell cycle
Endocrine system
Gene
Islet
Extracellular matrix
Endocrinology
Internal medicine
Pancreas
Biology
Insulin
Type 2 diabetes
Enteroendocrine cell

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