UJI TOKSISITAS FRAKSI n-HEKSAN DAUN BERUWAS LAUT (Scaevola taccada (Gaertn.) Roxb.) DENGAN METODE BRINE SHRIMP LETHALITY TEST

Research of effect toksisitas of n-heksan faction of the beruwas laut (Scaevola taccada (Gaertn.)Roxb.) leaf at prawn larva of Artemia salina Leach have been done as a mean to determine potency of toksisitas and value of LC­­­ 50 beruwas laut (Scaevola taccada (Gaertn.)Roxb.) leaf. As control used n-heksan. Before treatment, prawn egg of Artemia salina Leach incubated at some stage and after 48 hours prawn larva of Artemia salina Leach are ready to given treatment. Hereinafter n-heksan faction of beruwas laut (Scaevola taccada (Gaertn.)Roxb.) leaf with concentration 0,1 ; 1 ; 10 ; 100 µg/ml in sea water enhanced 10 prawn larvas. For control, done same treatment. Perception done after 24 hours treatment by counting dead prawn larva. Result of perception indicate that value of LC 50 n-heksan faction of beruwas laut (Scaevola taccada (Gaertn.)Roxb.) leaf 4,17 ± 2,59 µg/ml. So that can be expressed that n-heksan faction of beruwas laut (Scaevola taccada (Gaertn.)Roxb.) leaf have potency as anticancer, this matter is based by standard of Meyer (1982) expressing that a natural materials compound have potency of anticancer if value of LC 50 <1000 µg/ml.   Key word : Toksisitas Test , Scaevola taccada (Gaertn.)Roxb , Brine Shrimp Lethality Test