Genetic Mechanisms of Memory Disorders (Excluding Alzheimer's Disease)

In this chapter we consider human disorders of memory and their possible underlying genetic and molecular mechanisms. The genetic and molecular basis of Neurofibromatosis type I and other RASopathies, Angelman syndrome, Fragile X syndrome, Williams–Beuren syndrome, Down syndrome, Pitt-Hopkins syndrome, and Rett syndrome will be discussed. An overview of current research into suitable models of disease and treatment will provide insight into the value of basic scientific research in understanding human memory disorders and intellectual disabilities.