Immunohistochemical study of craniopharyngiomas.

Abstract The purpose of this study is to present the histological characteristics of tumor origin and proliferative characteristics of craniopharyngioma. In 25 craniopharyngiomas, the immunoperoxidase technique revealed strong positive reactions for keratin and cytokeratin in cytoplasm of tumor cells. But, immunostaining of keratin and cytokeratin differ from each of layer of craniopharyngioma. The ciliated epithelium in the craniopharyngioma was not stained by keratin, but ciliated epithelium of Rathke's cleft cyst was stained by cytokeratin.