Genetic defects in PRC2 components other than EZH2 are not common in myeloid malignancies

To the editor: Several genetic alterations affecting loci encoding epigenetic regulators have been discovered in myeloid malignancies in the last few years. Previously, we and others identified novel mutations in the histone methyltransferase gene EZH2 .[1][1][][2]–[3][3] EZH2 encodes the