QuantiFERON-TB Gold Plus: High qualitative and quantitative agreement between ELISA and CLIA assays.

QuantiFERON -TB Gold plus (QFT-plus) represents the latest generation of interferon-gamma release assays (IGRAs), eliciting a response from CD8 T- cells in addition to CD4-T cells, with the aim to improve detection of latent M.tuberculosis infection (LTBI) with respect to its predecessor QuantiFERON-TB Gold In-Tube (QFT-GIT), even if no significant differences have been shown between the two tests (1, 2).….