pH Stability, Response to Antibiotics and Factors Influencing Egg-Culture of Mumps Virus.

SummaryNeither penicillin nor streptomycin, separately or combined, caused demonstrable inhibition of the mumps virus in vitro or in vivo. Maximum virus infectivity occurred in 7-day-old embryos 4-6 days after inoculation; hemagglutinative capacity reached a maximum in like embryos after 8 days of incubation. The concentration of virus containing chorio-allantoic fluid used as inoculum had no apparent effect on growth of the virus in eggs. The range of optimum pH stability was 5.65 to 7.9, but the virus was relatively unstable under any conditions.