A case of solitary fibrous tumor/hemangiopericytoma in the central nervous system with papillary morphology

2019 
: This report describes the clinicopathological findings of a solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) of the central nervous system in a 59-year-old man with space-occupying lesions on both the left anterior basicranial and on the top tail of falx cerebri. The tumor showed small quantities of solid papillary areas and a prominent papillary structure, where atypical cells were compactly arranged along the fibrovascular core. The tumor cells of both components showed nuclear relocalization of the signal transducer and activator of transcription 6 protein, with very high specificity and sensitivity for the diagnosis of SFT/HPC. In the literature, only three cases of SFTs with a papillary pattern have been reported, but this case showed a complete papillary pattern. "Papillary" SFT/HPC is a rare morphological variant of SFTs/HPCs, and its differential diagnosis among intracranial tumors is an important factor which clinicians should bear in mind during diagnosis.
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