Reactive lymphoid hyperplasia – A case of castlemans disease reviewed

Abstract Reactive lymphoid hyperplasia is a common pathological finding from lung biopsy. It is frequently the original pathologic interpretation from FNA or core biopsies of lesions that are ultimately determined to be non-neoplastic pulmonary lymphoid disorders. One of these disorders is Castleman's Disease. We present a case of a 35-year-old male who underwent multiple procedures to diagnose a posterior mediastinal mass. This was eventually diagnosed as Castleman's Disease. We review the pathology of reactive lymph node hyperplasia and the spectrum of non-neoplastic pulmonary lymphoid disorders. We also review the Unicentric hyaline vascular variant form of Castleman's disease.