Stereoselective reductions of chalcones using biocatalyst – Daucus carota

Biocatalysis is an important area in terms the organic synthesis, where many of its features can be used to induce stereoselective synthesis of important pharmaceutical intermediates and several commercially available products. However, catalysts to induce asymmetry are not available to all, due to its high cost and reactions restrictions. Recent studies indicate that the use of vegetables available in our everyday can be an alternative to investigate its effectiveness in some stereoselective reduction with economic important and ecological implications. From the previously synthesized compound 1 was carried out methodological study aimed stereoselective reduction to its respective alcohol saturated with the intention of using it as a building block in the synthesis of compounds with activity from an methodology efficient and convergent.