Blood properties of rainbow trout in acute hepatotoxity by carbon tetrachloride.

The liver injury caused by carbon tetrachloride (CCI4) injection to dorsal aorta of rainbow trout, Salmo gairdneri irideus, was evaluated by the changes of some blood parameters. Whereas significant changes of plasma constituents by CCI4 injection were accompanied by the appearance of necrotic area in liver, the hematological values of affected specimens were nearly equal to those of normal ones. The electrophoretic examination showed depression of albumin fraction and lipoproteins in the CCI4-injected specimens. A compensational increase of certain globulin components in them was noticed. The plasma lipid level was observed to decrease with increasing dose in those specimens. The decrease of lipid was for the most part accounted for by the decrease of triglyceride fraction. No significant change was observed in the plasma cholesterol level.