Inflammation and microbiota fingerprint: Delphi's oracle for NAFLD-related HCC?

Dysfunctions of the gut bacterial flora have an important impact on liver diseases. Quantitative or qualitative ruptures of intestinal homeostasis, collectively termed dysbiosis, constitute an increasingly recognized associated factor for chronic liver diseases, including non-alcoholic fatty liver disease (NAFLD). The evidence that gut maladaptation is a common feature in NAFLD settings led Ponziani et al. to investigate whether specific variations of the flora and inflammatory cues are enriched in NAFLD patients presenting with HCC (Ponziani et al. this issue). This article is protected by copyright. All rights reserved.