Morphometric differences between normal and dry eyes.

The aim of the study was to quantify the anatomic differences in central corneal thickness, anterior ocular chamber depth, lens thickness, vitreous chamber depth, and ocular axial length between normal and dry-eyes. Central corneal thickness (CCT), ocular anterior chamber depth (ACD), lens thickness (LT), vitreous chamber depth (VCD) and ocular axial length (AL) were measured in 70 normal subjects and in 58 subjects with dry-eyes. Central corneal thickness was measured with scanning-slit corneal topography while ocular anterior chamber depth, lens thickness, vitreous chamber depth and ocular axial length were measured with applanation ultrasound biometry. Central corneal thickness was 0.558±0.30 mm and 0.532±0.34 mm in normal and dry-eyes, respectively (p<0.001). Mean ocular anterior chamber depth was 3.17±0.23 mm and 2.93±0.35 mm in normal and dry-eyes, respectively (p=0.002). Lens thickness was 4.49±0.42 mm in the dry-eye patients and 4.71±0.32 mm in the normal subjects (p=0.022). Vitreous chamber depth was 16.75±1.75 mm and 15.54±1.34 mm in normal and dry-eyes, respectively (p=0.001). Ocular axial length was 24.58±1.73 in normal subjects and 23.07±1.48 in dry-eye subjects (p<0.001). We conclude that quantitative ocular anatomy values are lower in dry-eye subjects