The Beneficial Effect of an Intra-articular Injection of Losartan on Microfracture-Mediated Cartilage Repair Is Dose Dependent:

Catherine A. Logan,Xueqin Gao,Hajime Utsunomiya,Alex C. Scibetta,Mika Talwar,Sudheer Ravuri,Joseph J. Ruzbarsky,Justin W. Arner,Dandan Zhu,Walter R. Lowe,Marc J. Philippon,Johnny Huard

The Beneficial Effect of an Intra-articular Injection of Losartan on Microfracture-Mediated Cartilage Repair Is Dose Dependent:

2021

Catherine A. Logan
Xueqin Gao
Hajime Utsunomiya
Alex C. Scibetta
Mika Talwar
Sudheer Ravuri
Joseph J. Ruzbarsky
Justin W. Arner
Dandan Zhu
Walter R. Lowe
Marc J. Philippon
Johnny Huard

Background:A previous publication demonstrated that the oral intake of losartan promoted microfracture-mediated hyaline-like cartilage repair in osteochondral defects of a rabbit knee model. Howeve...

Keywords:

tgf β signaling
Losartan
Pharmacology
cartilage repair
intra articular
dose dependence
Medicine

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