The effects of the Reinforcing Kidney and Activating Blood Recipe Affecting the Value of bc1-2,bax and caspase-3 in the Tissue of Corpus Cavernosum Smooth Muscle of DMED-Rats

Objective: Observing the effects of reinforcing kidney and activating blood recipe affecting the value of bc1-2,bax and caspase-3 in the tissue of corpus cavernosum Smooth muscle of DMED-rats.Methods: An animal model of diabetes was induced by a single intravenous dose of streptozotocin(STZ,60mg/kg body weight) in Wistar rats.Recording the numbers of penile erection of each rat by camera after subcutaneous inject of apomorphine(80mg/kg).Screening the model of STZ-rats with erectile dysfunction and grouping into 6 groups: control group,model group,Chinese Medicine group,low-dosage group,Diamicron group,Diamicron combined Testosterone Undecanoate group.After administrating 12 weeks,observed the value of bc1-2,bax and caspase-3 in the tissue of corpus cavernosum smooth muscle of DMED-rats.Results: The reinforcing kidney and activating blood recipe can improve the vulue of bc1-2,bax and caspase-3.Conclusion: The reinforcing kidney and activating blood recipe has regulatory function for bc1-2,bax and caspase-3 in the tissue of corpus cavernosum smooth muscle of DMED-rats.