Population Pharmacokinetics and Pharmacodynamics of Mitomycin During Intraoperative Hyperthermic Intraperitoneal Chemotherapy

Serge van Ruth,R. A. A. Mathot,Rolf W. Sparidans,Jos H. Beijnen,Vic J. Verwaal,F.A.N. Zoetmulder

Population Pharmacokinetics and Pharmacodynamics of Mitomycin During Intraoperative Hyperthermic Intraperitoneal Chemotherapy

2004

Serge van Ruth
R. A. A. Mathot
Rolf W. Sparidans
Jos H. Beijnen
Vic J. Verwaal
F.A.N. Zoetmulder

Background: During recent years, cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) with mitomycin has been used for various malignancies.

Keywords:

Hyperthermic intraperitoneal chemotherapy
Anesthesia
Route of administration
Pharmacodynamics
Antibiotics
Body surface area
Pharmacology
Population
Chemotherapy
Pharmacokinetics
Medicine
cytoreductive surgery
population pharmacokinetics
Pharmacotherapy
Surgery

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