MIGRATION OF CHARGED SPECIES IN LIPID BILAYER MEMBRANES UNDER AN ELECTRIC FIELD

This paper reviews recent progress in studies on the migration of charged species, including charged lipids, membrane-attached proteins and vesicles, and integrated membrane proteins, in lipid bilayer membranes under an external electric field. The migration of these charged substances is controlled by the interplay of electrophoresis and electroosmosis. This phenomenon can be employed to separate the charged lipids and membrane-attached proteins, and concentrate integrated membrane proteins.