Abstract 19812: Endothelial Dysfunction is Associated With Cardiovascular Events in Male Patients After ST-Segment Elevation Myocardial Infarction

Introduction: Endothelial dysfunction plays a pivotal role in the progression of atherosclerosis and subsequent cardiovascular events. Advanced endothelial dysfunction in patients with stable coronary disease is known to be significantly correlated with near future cardiovascular events. However, the prognostic value of endothelial dysfunction in patients with ST-segment elevation myocardial infarction (STEMI) is unclear. Hypothesis: We assessed the hypothesis that endothelial dysfunction is associated with an increased risk of secondary cardiovascular events in patients with STEMI. Methods: A total of 220 male patients with STEMI were enrolled. We assessed peripheral endothelial function by reactive hyperemia peripheral arterial tonometry (RH-PAT) as RH-PAT index (Ln-RHI). The patients were divided into low and high endothelial function groups using the median value of Ln-RHI. Low endothelial function was defined as Ln-RHI ≤ 0.565. All patients were followed for cardiovascular events, which consist of de...