Thrombogenesis and its treatment in portal system after devascularization

Objective To discuss the occurrence of thrombosis in portal system of patients with cirrhotic portal hypertension after devascularization and the methods for treatment and prevention. Methods The clinical data of 113 patients with cirrhotic portal hypertension after the devascularization were collected and analyzed retrospectively,and the occurrence time,parts as well as the treatment and prevention methods were discussed. Results Among the 113 patients,33 of them were found with thrombosis in their portal system,and the occurrence rate was 29.2%. The occurrence time of thrombosis was 2-15 days post-devascularization,and the median time was 6 days post-operation. Among the 33 cases with thrombosis,there were 19 cases of splenic vein thrombosis,10 cases of portal thrombosis,and 4 cases of both of them. After the thrombolytic therapy,the thrombosises in 30 cases disappeared. Conclusions Most of the thrombosises in portal system happen in splenic vein post-devascularization. Avoiding clamping the trunk of splenic vein in the operation and taking thrombolytic therapy at the early stage after the operation can effectively prevent the occurrence of thrombosis.