Immunoglobulins in pernicious anaemia. Including a report on a patient with pernicious anaemia, IgA deficiency and an M component of kappa-type IgG.

. Determinations have been made of the concentrations of serum total protein, electrophoretic fractions and immunoglobulins A, G and M in 11 patients with pernicious anaemia (PA) before and after treatment with vitamin B12 and in 22 other patients with PA who had already received treatment. During the course of treatment a tendency was observed to increasing values of the serum globulin fractions and IgG. All the sera were subjected to immunoelectrophoresis. One patient with slight IgA deficiency exhibited a presymptomatic myeloma (monoclonal gammopathy) of the IgG, kappa-type.