Design, synthesis, characterization and antitubercular activity of some 2-heterocycle-substituted phenothiazines

Some novel 2-heterocycle-substituted phenothiazines having a pyrazolo(3,4-d)pyrimidine nucleus have been synthesized by using the Biginelli multi-component cyclocondensation reaction. The products were characterized by FT-IR, 1 H NMR, 13 C NMR, mass spectra and elemental analysis. The products were evaluated for their antitubercular activity against Mycobacterium tuberculosis H37 Rv.