Atorvastatin Decreases Cellular Proliferation and Bone Matrix Expression in the Hypercholesterolemic Mitral Valve

To the Editor: Idiopathic calcification of the mitral annulus is one of the most common cardiac abnormalities demonstrated at autopsy ([1][1]). Currently, the pathophysiology of mitral annular calcification (MAC) is viewed as a passive degenerative process due to a buildup of calcium along the