Антимикробная и противогрибковая активность арглабина и его аналогов

The purpose of this work was to study the antimicrobial and antifungal activity of sesquiterpene lactones and their derivatives. As result of the studies we established for the first time the antimicrobial and antifungal activity of sesquiterpene lactones and their derivatives. Bromocarbene derivative of Arglabin inhibits Вас. subtilis strains at low doses affecting peptidoglycan in thin-walled strains of gram-negative bacilli. Arglabin and its analogues inhibits grows of pathogenic fungi (Aspergillus flavus, Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum cams).