Comment on Genuth. Should sulfonylureas remain an acceptable first-line add-on to metformin therapy in patients with type 2 diabetes? No, it's time to move on! Diabetes Care 2015;38:170-175.
2015
Genuth (1) discusses in a Counterpoint article several arguments against the use of sulfonylureas (SUs) as an add-on therapy to metformin. We understand that in this format he makes arguments against the use of SUs; however, we could not appreciate his oversimplification by ignoring within-class differences. Specifically, the safety of gliclazide is not recognized.
In the 2013 Dutch type 2 diabetes guidelines from the …
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