Synthesis and study antimicrobial activity of polybarbiturate contain triazole ring

2020 
A series of Polybarbiturate containing triazole ring were prepared via the click reaction of diazido barbiturate and dipropargyl barbiturate in the presence of CuCl and Sodium ascorbate. The structures all prepared polymers were identified by using NMR and IR techniques. In aprotic polar solvents such as DMF and DMSO the end products showed that polymers have high solubility at low temperatures. Thermal stability of the all polymers were determined using thermo gravimetric analysis (TGA) and differential scanning calorimetry (DSC) which indicated that they have high Tg (124–175 °C) and good thermal stability under N2 atmosphere. The synthesized polymers were evaluated antimicrobial activity against different types strains of Gram-negative and positive bacteria and showed good significant against these bacteria.
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