Effect of ketamine anaesthesia on middle ear pressure in rabbits: a pilot study

Tavflanlarda orta kulak bas›nc› uzerine ketamin anestezisinin etkisi: pilot cal›flma Amac: Anestezik maddelerin orta kulak bas›nc› uzerine etkileri hak- k›ndaki cal›flmalar›n cou gazlarla yap›lm›fl olmas›na ramen, keta- minin orta kulak bas›nc› uzerine etkisi hakk›nda herhangi bir cal›fl- ma bildirilmemifltir. Bu cal›flman›n amac› ketaminin orta kulak bas›n- c› uzerine etkisini deerlendirmektir. Abstract Objectives: Although most studies about effect of anaesthetics on middle ear pressure were explained with gas effect there are no studies about effect of ketamine on middle ear pressure. The aim of this study was to evaluate the effect of ketamine anaesthesia on middle ear pressure. Methods: Male New Zealand rabbits (n=15), weighing between 2.5-3.2 kg were randomly divided into two groups. Those in Group I (n=9) were anaesthetized by intravenous ketamine 50 mg.kg-1 whilst Group II (n=6) were injected with the same volume of saline. Baseline tympanometry readings were performed on the left and right ears after otoscopy examination and again at 5 and 20 min- utes.