Идентификация и локализация стволовых клеток в органах дыхательной системы (обзор литературы)

The cellular mechanisms regulating the replacement of dying differentiated cells are one of the basic questions in research of respiratory system epithelium reparation after the damage. Numerous works in this field have shown that airways epithelium is presented by two pools of cell-predecessors: a basal cell and a specialized secretory cell which is similar to Clara cell. Morphological and functional analyses of processes of airways epithelium reparation after the influence of various damaging factors have allowed to identify the above-stated cell as proponents of highly differentiated elements.