Effect of c-MYC and E2F1 Gene Silencing and of 5-Azacytidine Treatment on Telomerase Activity in Pancreatic Cancer-Derived Cell Lines

Alpana Kumari,Radhika Srinivasan,Jai Dev Wig

Effect of c-MYC and E2F1 Gene Silencing and of 5-Azacytidine Treatment on Telomerase Activity in Pancreatic Cancer-Derived Cell Lines

2009

Alpana Kumari
Radhika Srinivasan
Jai Dev Wig

Background: The gene promoter region of human telomerase reverse transcriptase (hTERT) contains binding sites for c-myc and E2F1 as well as CpG islands, suggestin

Keywords:

Gene silencing
Bisulfite sequencing
CpG site
Telomerase reverse transcriptase
Telomerase
Cancer research
Promoter
Medicine
Reverse transcriptase
E2F1
Molecular biology
Methylation
Cell culture

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