Translational research of VOLTAGE-A: Efficacy predictors of preoperative chemoradiotherapy and consolidation nivolumab in patients with both microsatellite stable and microsatellite instability-high locally advanced rectal cancer.

Koji Inamori,Yosuke Togashi,Hideaki Bando,Yuichiro Tsukada,Shota Fukuoka,Ayako Suzuki,Yutaka Suzuki,Daisuke Kotani,Motohiro Kojima,Makoto Fukui,Satoshi Yuki,Yoshito Komatsu,Shigenori Homma,Akinobu Taketomi,Mamoru Uemura,Takeshi Kato,Masaaki Ito,Hiroyoshi Nishikawa,Takayuki Yoshino

Translational research of VOLTAGE-A: Efficacy predictors of preoperative chemoradiotherapy and consolidation nivolumab in patients with both microsatellite stable and microsatellite instability-high locally advanced rectal cancer.

2021

Koji Inamori
Yosuke Togashi
Hideaki Bando
Yuichiro Tsukada
Shota Fukuoka
Ayako Suzuki
Yutaka Suzuki
Daisuke Kotani
Motohiro Kojima
Makoto Fukui
Satoshi Yuki
Yoshito Komatsu
Shigenori Homma
Akinobu Taketomi
Mamoru Uemura
Takeshi Kato
Masaaki Ito
Hiroyoshi Nishikawa
Takayuki Yoshino

100Background: In VOLTAGE-A, chemoradiotherapy (CRT; 50.4Gy with capecitabine, 1,650mg/m2) followed by five cycles of consolidation nivolumab (nivo) (240mg q2 weeks) showed 30% pathological complet...

Keywords:

Microsatellite instability
Oncology
locally advanced
Internal medicine
Colorectal cancer
Translational research
Capecitabine
in patient
Nivolumab
Chemoradiotherapy
Medicine

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