Synthetic process of medical intermediate1,4,5,6-tetrahydronaphthalene-3-H-cyclopenta-carbonitrile

The invention provides a synthetic process of a medical intermediate 1,4,5,6-tetrahydronaphthalene-3-H-cyclopenta-carbonitrile. The synthetic process comprises the following steps: (1) cyclization reaction; (2) hydrolysis reaction; (3) amidation reaction; and (4) dehydration reaction. Cyclopentanone is adopted as a raw material, and the 1,4,5,6-tetrahydronaphthalene-3-H-cyclopenta-carbonitrile is obtained in manners of cyclization, hydrolysis, amidation and dehydration. The synthetic process has the advantages of low cost, mild reaction condition, low toxicity, convenient technological operation and the like.