Short-term itraconazole versus terbinafine in the treatmentof superficial dermatomycosis of the glabrous skin(tinea corporis or cruris)

Dermatomycoses can be treated effectively with oral griseofulvin or ketoconazole but the necessity for relatively long-term therapy and the significant incidence of gastrointestinal complaints and headache have restricted the use of these agents to recalcitrant infections [1-9]. Itraconazole (Sporanox®, Janssen, Beerse, Belgium) is a triazole derivative that potently inhibits the cytochrome P450-dependent enzyme, 14alpha-demethylase [...]