Retention of the NLRP3 Inflammasome-primed Neutrophils in the Bone Marrow is Essential for Myocardial Infarction-induced Granulopoiesis.

Gopalkrishna Sreejit,Sunil Kiran Nooti,Robert M Jaggers,Baskaran Athmanathan,Ki Ho Park,Annas Al-Sharea,Jillian Johnson,Albert Dahdah,Man K.S. Lee,Jianjie Ma,Andrew J. Murphy,Prabhakara R. Nagareddy

Retention of the NLRP3 Inflammasome-primed Neutrophils in the Bone Marrow is Essential for Myocardial Infarction-induced Granulopoiesis.

2021

Gopalkrishna Sreejit
Sunil Kiran Nooti
Robert M Jaggers
Baskaran Athmanathan
Ki Ho Park
Annas Al-Sharea
Jillian Johnson
Albert Dahdah
Man K.S. Lee
Jianjie Ma
Andrew J. Murphy
Prabhakara R. Nagareddy

Background: Acute myocardial infarction (MI) results in overzealous production and infiltration of neutrophils to the ischemic heart. This is mediated in-part by granulopoiesis induced by the S100A...

Keywords:

Inflammasome
Medicine
Granulopoiesis
infiltration
Myocardial infarction
ischemic heart
Pathology
Bone marrow

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