Merkel Cell Carcinoma: A Case Report

Merkel cell carcinoma is a rare cutaneous undifferentiated carcinoma. The optimal management of Merkel cell carcinoma has not been clearly defined. We report a patient, who was a 74-year-old man with a 4×4 cm reddish nodule at left thigh. Skin biopsy was performed and the diagnosis of Merkel cell carcinoma was made by electron microscopic and immunohistochemical examination. Then, wide local excision and split thickness skin graft was performed. The magnetic resonance imaging demonstrated residual tumor. Radiation therapy to the left thigh and ipsilateral inguinal area was instituted two months after surgery. We review the electron microscopic and immunohistochemical findings and also describe the effect of radiation therapy for this case.