Oleanolic acid derivatives, preparation method and use thereof has anti-cancer
2012
The present invention belongs to the technical field antineoplastic drugs, provides oleanolic acid derivative having the structure of Formula Ⅰ, wherein R1 is hydrogen, C1-C4 linear or branched alkyl; R2 is halogen, hydroxy, C1-C4 linear chain or branched alkyl, C1-C4 linear or branched alkoxy group. The present invention also relates to a method for preparing the above compounds, and also discloses a pharmaceutical composition of the active compound as an active ingredient, as well as their use in anti-cancer drugs.
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