EVALUATION OF ATRIAL ELECTROMECHANICAL DELAY IN SILENT CEREBRAL ISCHEMIA PATIENTS

Objective: Silent cerebral ischemia (SSI) is found on cranial imaging, with no signs of stroke and has similar risk factors as stroke. There are few studies evaluating the relationship between SSI and AF. In this study, we aimed to evaluate left atrial functions and atrial mechanical delay (AED) in SSI cases with noninvasive tissue doppler imaging (TDI). Method: 39 SSI and 29 healthy subjects as control group included in this study. Atrial conduction times calculated by Tissue Doppler Imaging (TDI), demographic features, laboratory findings, ECG, transthoracic ECO were recorded. AED was calculated by measuring the lateral mitral annulus (PA lateral), septal mitral annulus (PA septum) and right ventricular tricuspid annulus (PA tricuspid) by TDI. Left atrial volumes were measured in the apical fourchamber view with the disk method. Left atrial mechanical functions were evaluated. The heart rate variability parameters of the patient group were compared by the holter. Results: The mean age of 39 patients (32K/7E) was 51 ± 10 years and the mean age of 29 healthy controls (24K/5E) was 48.8±5.9 years. There was no difference between the two groups in demographic characteristics (p>0,05). Blood glucose was significantly higher in the SSI group (p=0.034). Parameters related to AED were not statistically significant in the SSI group but were found longer (p>0.05). The parameters of left atrial function such as LAPEF (0,3±0,1 versus 0,2±0,1, p=0,050), LAPEV (12,1± 6,8 versus 10,3±8, p=0,197) and LATEV (23,6±11,1 versus 21,6±9,4 p=0,496) were higher but were not statistically significant. Conduit volum (26,8±12,7 versus 21,5±16,5, p=0,017), LVEDV (91,8±24,4 versus 74,8±25,3. P=0,002) and LVESV (41,4±13,4 versus 31,7,8±15,7. P=0,003) was found statistically significant. Conclusion: Regulation of blood glucose of SSI cases and follow-up the patienst for cardiac diastolic functions, and taking into consideration that these changes may lead to prolongation at the time of atrial conduction are important.