Plasma lipoprotein levels and functional status of thrombocytes in patients with ischemic heart disease during treatment with essential phospholipids

Variations in platelet aggregation activity before and after the control of lipid metabolism with lecithin linoleate (essential preparation, 1800 mg EPL daily) were examined in coronary patients with pronounced hyperlipidemia. A considerable change was noted in the ratios of LP fractions, that is, rising HDLP in the presence of decreasing total plasma lipids, Changes in plasma lipid composition were accompanied with a reduction of platelet aggregation activity that persisted for 3 months following the discontinuation of the drug. Correlation and regression analyses of relationships between platelet aggregation and HDLP levels were carried out.