A novel hybrid macrocyclic receptor based on bile acid and calix[4]arene frameworks for metal ion recognition

Abstract A novel hybrid macrocyclic receptor based on bile acid and calix[4]arene has been synthesized using the α-face of the bile acid and cone-conformation of calix[4]arene. Metal recognition properties of receptor were investigated. The receptor showed the strongest affinity for Hg 2+ in acetonitrile. The stoichiometry of the Receptor:Hg 2+ was 1:1.