Clinical assessment of diclofenac sodium eyedrops in controlling postoperative reaction of laser subepithelial keratomileusis

Objective To evaluate the efficacy and safety of diclofenac sodium eyedrops for reducing postoperative ocular pain and inflammation of laser subepithelial keratomileusis(LASEK). Methods Seventy-five patients (150 eyes) were observed by self-contrast(L vs R). One eye treated with diclofenac sodium eyedrops was regard as test group,the fellow eye treated with normal eyedrops as self-contrast group.All patients were followed up for 1 month. Results There was a statistically significant difference of reducing postoperative ocular pain and inflammation of LASEK between the two groups (P<0.01).No severe complications were found in study group. Conclusions Diclofenac sodium eyedrops is an effective and safety drug in reducing postoperative ocular pain and inflammation. Key words: Laser subepithelial keratomileusis; Diclofenac sodium; Corneal irritation