Synthesis of Potential Anti-AIDS Amphiphiles. A New Efficient Acylation of Amino-Naphthalene Disulfonic Acid Derivatives
1993
Abstract We describe a new synthetic route to amphiphilic derivatives of naphthalene disulfonic acid which have been found to be active against HIV-1 and HIV-2. The compounds were obtained in good yield by a new efficient acylation of amino-naphthalene disulfonic acid using N-acyl-thiazolidine-2-thiones as acylating agents.
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