Eco-friendly atom-economical synthesis of 2-substituted-benzo[d]thiazoles and 2-substituted-benzo[d]oxazoles using 2-acylpyridazin-3(2H)-ones
2013
Abstract Efficient and green syntheses of heterocycles are of great importance. In this work, we have demonstrated the synthesis of benzo[ d ]thiazoles and benzo[ d ]oxazoles using 2-acylpyridazin-3(2 H )-ones as acyl transfer agents under transition-metal-free and eco-friendly conditions. It is worthy to note that the reaction is efficient, green, and economical, and will find several applications in organic synthesis, medicinal chemistry, and industrial chemistry.
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