Physicochemical and functional characterization of trastuzumab-dkst, a trastuzumab biosimilar.

Parag Goyal,Jyoti Iyer,Laxmi Adhikary,Bhavesh Vats,Pradeep Kabadi,H. Pai,Daniel J. Ranayhossaini,Shankara Gouda,Malini Subbarao,Gaurav R Mehta,Arindam Saha,Arnab Bera,Abhilashi Sahu,Maninder Kaur,Ankita Singh,Ashwani Marwah,Praveen Kumar Reddy Moole,Jeffrey Smith,Ramakrishnan Melarkode,Rajesh Ullanat

Physicochemical and functional characterization of trastuzumab-dkst, a trastuzumab biosimilar.

2021

Aims: Preclinical comparative similarity studies of trastuzumab-dkst, a Herceptin® biosimilar, are reported. Materials & methods: Primary sequence and higher order structure and pharmacological mec...

Keywords:

primary sequence
Trastuzumab
Bioequivalence
Biosimilar
Cancer
Breast cancer
Similarity (network science)
Medicine
Computational biology
Higher Order Structure

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