Characteristics and outcome of AKI needing dialysis with COVID-19 infection

Background: COVID-19 infection has varying grades of mortality worldwide Multi-organ injury, not uncommonly associated with AKI, portends a poor outcome We studied AKI needing hemodialysis (HD) in the context of COVID-19 infection Methods: From March 15th to May 25th 2020, for consecutive COVID-19 infections AKI needing HD in a large dialysis network age, gender, payer type, days:admission to HD start, urine output, S Cr, comorbidities, other organ injuries, length of stay & outcome, dialysis session details: blood flow rate(BFR), dialysis flow rate(DFR), ultafiltration volume were reviewed We compared survivors and non survivors using Mann Whitney/ Wilcoxon 2 sample test for medians and Fisher exact 2 tailed for association Results: n = 20 Mean age: 56 7 + 3 93 years M:F 17:3, 9 survived, 11 expired HD sessions=51;CRRT: 4, duration: 29 2 ± 25 4 hours 47 sessions: Duration: 4 87 ± 1 11 hours, BFR: 195 ± 43 ml/min, DFR: 389 ±99 ml/mn, UF: 437ml/hour No clotting reported Conclusions: AKI needing HD in COVID-19 infection is associated with significant multiorgan injury and high mortality;middle aged male predominate No significant clinical characteristics were predictive of survival in a sample size