Notice of Retraction Butachlor Disrupts Thyroid Hormones on Early Life Stage of Zebrafish (Danio rerio)
2011
Butachlor, as a chloracetamide herbicide, is widely used in China. In the present study, zebrafish (Danio rerio) embryos were exposed to different concentrations of butachlor (0, 25, 50, 100 μg L -1 ) for 30 d, to determine the effects on the hypothalamo-pituitary-thyroid axes. Seven different endpoints were examined: whole-body T 4 and T 3 , TRH and TSH contents, body growth (weight and fork length) and condition factor. The results indicated that butachlor did not affect the mortality, mean length and the contents of TRH and TSH in juveniles, while significantly increased the mean weight, condition factor and the contents of T 4 and T 3 , suggesting that butachlor might be a thyroid disrupter.
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