Increased tissue contrast by high resolution simultaneous dual-band optical coherence tomography in three dimensions

Enhanced visualization of tissue contrast and morphological boundaries is demonstrated by analyzing OCT volume data in two distinct wavelength regions. The extension of this so-called simultaneous dual-band method to three dimensions is realized by a custom-built 3D spectral domain OCT system imaging in the 800 und 1200 nm wavelength domain. Color representations of the spectral differences of high resolution OCT volume data significantly simplify the discrimination of different tissue structures beyond the capabilities of cross-sectional spectroscopic OCT approaches.