INFLUENCE OF NEONATAL HYPOTHYROIDISM ON ADRENAL TYROSINE HYDROXYLASE ACTIVATION IN THE YOUNG RAT

SUMMARY 1. Adrenal TH activation was elicited in young rats (aged 4,6 and 14 days) by insulin hypoglycaemia. In the control rats, TH activation varied between 125 and 147% above basal values. 2. Neonatal hypothyroidism induced by PTU treatment impaired TH activation. Compensatory treatment with T3 to the PTU-treated young rats led to a return to control activation.